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Date: 11-Mar-2008

Research Scientist I

Specific Responsibilities: - Conceive, design and execute reaction
sequences and define processes to chemical intermediates and drug
substances; - Conduct route scouting, reaction optimization, and scale-
up demonstration; - Perform chemical reactions, isolations,
separations, purifications and crystallizations; - Write concise and
detailed procedures and reports in support of patent applications,
regulatory filings, and Technology Transfers; -participate in project
teams and communicate thoughts, ideas, results and status;

- Ph.D. required. - Skill in the art and practice of modern synthetic
and mechanistic organic chemistry. - Practical experience in multi-
step syntheses. - Understanding and competence with modern
spectroscopic methods applied to structure determination including 1H
and multinuclear NMR, infra-red spectroscopy, and mass spectroscopy. -
Experience in the use of preparative silica gel chromatographic
separations as well as analytical separations involving HPLC and GC. -
Experience with spreadsheet programs such as Microsoft Excel and
database software such as SciFinder is a plus. Essential Duties and
Job Functions: Responsible for conducting scientific research for the
discovery of drugs, the development of drug candidates or the research
support of marketed drugs. Applies the principles and techniques of
related scientific specialty to potential inventions, products and
problems. Works under supervision of more senior scientists or
scientific directors to identify and validate targets, advance the
development of economical, state-of-the art techniques to isolate
characterize, purify and mass-produce substances, reagents, assays and
tools in an effort to discover therapeutic bioproducts to make such
substances available as tools for other research projects. Working
under general supervision, plans designs, implements and analyzes
laboratory experimentation to advance scientific knowledge of drug
substances or techniques to identify such substances. May advise
research associates or members of project teams in the initiation and
execution of laboratory experimentation, considering economic and
safety factors. Participates in development of patent applications.
Participates in group meetings. Presents results of work, interprets
data, draws conclusions regarding presented material and nature of
work. May make contributions to scientific literature and conferences
through publication and presentation of research results. May act as a
resource or provide work direction for other research personnel within
the company. Knowledge, Experience and Skills: Typically requires a
PhD in appropriate scientific discipline and 2 years of relevant
experience that indicates an aptitude to make significant
contributions within specialty and sustained strong performance and
accomplishments that align to company goals. Excellent communication
skills (both verbal and technical) and strong interpersonal skills are
required. Must be able to participate in highly effective teams.
Demonstrates emerging ability in developing methods, techniques and
evaluation criteria for obtaining results and interpreting
experimental outcomes. Maintains full working knowledge of state-of-
the art principles and theories, applying such knowledge to the
research direction that supports Company interests. Demonstrates
technical proficiency, scientific creativity, collaboration with
others and independent thought in suggesting experimental design and
research strategy. Must think critically and creatively and be able to
work independently, determine appropriate resources for resolution of
problems and have strong organizational and planning skills.

Thank you,
BioTech FYI Center
http://biotech.fyicenter.com/