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Thermodynamic change, amino acids to a protein.

 
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Jint Lynn
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PostPosted: Sun Mar 16, 2008 2:59 am    Post subject: Thermodynamic change, amino acids to a protein. Reply with quote

Here is the original question. It talks about thermodynamic change.
Sorry for my poor English.
_____________________________________________________________________
When a protein forms from amino acids, the following changes apply:
A)+ÄH, -ÄS, +ÄG
B)+ÄH, -ÄS, -ÄG
C)+ÄH, +ÄS, +ÄG
D)-ÄH, -ÄS, +ÄG
E)-ÄH, +ÄS, +ÄG
ANS:A

(PS. Ä=delta, I don't why the symbol could not be showed correctly in
my last post)
______________________________________________________________________
Why? Who can explain it?

Thank for your reply.
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Bob
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PostPosted: Sun Mar 16, 2008 9:07 pm    Post subject: Re: Thermodynamic change, amino acids to a protein. Reply with quote

On Sat, 15 Mar 2008 19:59:43 -0700 (PDT), Jint Lynn
<gplynn.leu@gmail.com> wrote:

Quote:
Here is the original question. It talks about thermodynamic change.
Sorry for my poor English.
_____________________________________________________________________
When a protein forms from amino acids, the following changes apply:
A)+?H, -?S, +?G
B)+?H, -?S, -?G
C)+?H, +?S, +?G
D)-?H, -?S, +?G
E)-?H, +?S, +?G
ANS:A

(PS. ?=delta, I don't why the symbol could not be showed correctly in
my last post)

Ah, got it. The problem is not English, but computer. Usenet (these
groups) use basic ASCII, and Greek letters (and many other "special
characters") do not come through (at least for many users).

One solution is to use d for delta -- and then say so, just as you did
above.


Ok, now to the question...

Think about how protein is made and broken down. Which process is
"spontaneous", (favorable) and which requires energy? This tells you
the sign of dG.

The sign of S is also "intuitive" -- at least if one does not try to
make it too hard. (dS can be complex, but is not in this case.) A
simple view of S relates to ordering. Which is more "ordered" and
which is more "constrained"? That gives you the sign of dS.

I'm not sure of an easy way to "guess" the sign of dH. Some
combinations of signs for dG and dS will dictate what the sign of dH
must be, but that won't help here. Perhaps someone else will come up
with something. Are you sure someone (book?) didn't drop a hint on
this? In any case, the sign for dH turns out to be the same as the
sign for dG. But I cannot offer a reason offhand, other than it is
measured.


bob
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